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A map depicting the relative order of a linked library of overlapping clones representing a complete chromosomal segment..
Industry:Biology
The effort to determine the 3D structures of large numbers of proteins using both experimental techniques and computer simulation.
Industry:Biology
Artificially constructed cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into E. coli; this permits cloning of larger DNA fragments (up to 45kb) than can be introduced into bacterial hosts in plasmid vectors..
Industry:Biology
In genetics, a type of mutation due to replacement of one nucleotide in a DNA sequence by another nucleotide or replacement of one amino acid in a protein by another amino acid.
See also: mutation.
Industry:Biology
The study of macromolecules important in biological inheritance..
Industry:Biology
The breaking during meiosis of one maternal and one paternal chromosome, the exchange of corresponding sections of DNA, and the rejoining of the chromosomes. This process can result in an exchange of alleles between chromosomes.
See also: recombination.
Industry:Biology
The treatment of injury or disease at the molecular level. Examples include the use of DNA-based diagnostic tests or medicine derived from DNA sequence information..
Industry:Biology
The study of the physical appearance of chromosomes.
See also: karyotype.
Industry:Biology
The group or recognizable pattern of symptoms or abnormalities that indicate a particular trait or disease..
Industry:Biology
